7-dehydrocholesterol reductase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9UBM7. Use UniProt Q9UBM7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UBM7 as the stable identity anchor, then attach disease evidence before program review.
7-dehydrocholesterol reductase
Review this target as 7-dehydrocholesterol reductase, mapped to UniProt Q9UBM7. Sequence length is 475 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 7-dehydrocholesterol reductase as ChEMBL target CHEMBL2169735, mapped to UniProt Q9UBM7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 7-dehydrocholesterol reductase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UBM7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 7-dehydrocholesterol reductase |
| UniProt Accession | Q9UBM7 |
| Component Type | Protein |
| Sequence Length | 475 aa |
7-dehydrocholesterol reductase
Review this target as 7-dehydrocholesterol reductase, mapped to UniProt Q9UBM7. Sequence length is 475 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5281526 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL2172347 | 8.64 | IC50 | 2.3 | Preclinical |
| CHEMBL5653589 | 8.26 | Kd | 5.497 | Preclinical |
| CHEMBL3752910 | 7.85 | Kd | 14.22 | Preclinical |
| CHEMBL5284923 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL2172349 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL2172263 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL5285995 | 5.97 | IC50 | 1070.0 | Preclinical |
| CHEMBL4454956 | 5.86 | IC50 | 1390.0 | Preclinical |
| CHEMBL5270628 | 5.69 | IC50 | 2040.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 4 | 6.8 |
| single protein format | 2 | 9 | 6.6 |