Bromodomain-containing protein 1 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt O95696. Use UniProt O95696 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O95696 as the stable identity anchor, then attach disease evidence before program review.
Bromodomain-containing protein 1
Review this target as Bromodomain-containing protein 1, mapped to UniProt O95696. Sequence length is 1058 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Bromodomain-containing protein 1 as ChEMBL target CHEMBL2176774, mapped to UniProt O95696. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Bromodomain-containing protein 1 is the right protein anchor across sources, using UniProt O95696 as the stable mapping.
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| Preferred Name | Bromodomain-containing protein 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O95696 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Bromodomain-containing protein 1 |
| UniProt Accession | O95696 |
| Component Type | Protein |
| Sequence Length | 1058 aa |
Bromodomain-containing protein 1
Review this target as Bromodomain-containing protein 1, mapped to UniProt O95696. Sequence length is 1058 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4086276 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL3774575 | 7.92 | Kd | 12.0 | Preclinical |
| CHEMBL5715923 | 7.92 | Kd | 12.0 | Preclinical |
| CHEMBL4086276 | 7.44 | Kd | 36.0 | Preclinical |
| CHEMBL4075478 | 7.43 | IC50 | 37.0 | Preclinical |
| CHEMBL3752151 | 7.34 | IC50 | 46.0 | Preclinical |
| CHEMBL4102050 | 7.32 | IC50 | 48.0 | Preclinical |
| CHEMBL4086958 | 7.29 | IC50 | 51.0 | Preclinical |
| CHEMBL4104538 | 7.28 | IC50 | 53.0 | Preclinical |
| CHEMBL4067968 | 7.21 | IC50 | 61.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 80 | 40 | 6.0 |
| assay format | 28 | 54 | 6.7 |
| cell-based format | 8 | 13 | 5.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 1 | 5.9 |
| cell-based format | 1 | 0 | — |