ATPase family AAA domain-containing protein 2B · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9ULI0. Use UniProt Q9ULI0 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9ULI0 as the stable identity anchor, then attach disease evidence before program review.
ATPase family AAA domain-containing protein 2B
Review this target as ATPase family AAA domain-containing protein 2B, mapped to UniProt Q9ULI0. Sequence length is 1458 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats ATPase family AAA domain-containing protein 2B as ChEMBL target CHEMBL2176775, mapped to UniProt Q9ULI0. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | ATPase family AAA domain-containing protein 2B |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9ULI0 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | ATPase family AAA domain-containing protein 2B |
| UniProt Accession | Q9ULI0 |
| Component Type | Protein |
| Sequence Length | 1458 aa |
ATPase family AAA domain-containing protein 2B
Review this target as ATPase family AAA domain-containing protein 2B, mapped to UniProt Q9ULI0. Sequence length is 1458 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4206758 | 9.0 | Kd | 1.0 | Preclinical |
| CHEMBL5079885 | 8.1 | Kd | 7.943 | Preclinical |
| CHEMBL4449894 | 7.7 | Kd | 19.95 | Preclinical |
| CHEMBL4536031 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL3590408 | 7.4 | Ki | 39.81 | Preclinical |
| CHEMBL3590408 | 7.0 | Kd | 100.0 | Preclinical |
| CHEMBL3590405 | 6.78 | Kd | 166.9 | Preclinical |
| CHEMBL4583297 | 6.3 | IC50 | 501.19 | Preclinical |
| CHEMBL3823478 | 6.0 | Kd | 1000.0 | Preclinical |
| CHEMBL4786330 | 5.28 | Kd | 5200.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 25 | 15 | 5.4 |
| single protein format | 22 | 31 | 4.8 |
| cell-based format | 5 | 1 | 7.0 |