Sentrin-specific protease 2 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q9HC62. Use UniProt Q9HC62 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9HC62 as the stable identity anchor, then attach disease evidence before program review.
Sentrin-specific protease 2
Review this target as Sentrin-specific protease 2, mapped to UniProt Q9HC62. Sequence length is 589 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sentrin-specific protease 2 as ChEMBL target CHEMBL2176776, mapped to UniProt Q9HC62. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sentrin-specific protease 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9HC62 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sentrin-specific protease 2 |
| UniProt Accession | Q9HC62 |
| Component Type | Protein |
| Sequence Length | 589 aa |
Sentrin-specific protease 2
Review this target as Sentrin-specific protease 2, mapped to UniProt Q9HC62. Sequence length is 589 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4791433 | 6.25 | IC50 | 560.0 | Preclinical |
| CHEMBL4776158 | 6.16 | IC50 | 690.0 | Preclinical |
| CHEMBL4781794 | 5.96 | IC50 | 1100.0 | Preclinical |
| CHEMBL4792569 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL4780770 | 5.85 | IC50 | 1400.0 | Preclinical |
| CHEMBL4780586 | 5.8 | IC50 | 1600.0 | Preclinical |
| CHEMBL5175111 | 5.7 | IC50 | 2000.0 | Preclinical |
| CHEMBL4796113 | 5.66 | IC50 | 2200.0 | Preclinical |
| CHEMBL2009952 | 5.64 | IC50 | 2300.0 | Preclinical |
| CHEMBL4778045 | 5.64 | IC50 | 2300.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 22 | 5.4 |
| assay format | 3 | 2 | 5.6 |
| cell-based format | 2 | 54 | 5.1 |