Polycomb protein EED · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O75530. Use UniProt O75530 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O75530 as the stable identity anchor, then attach disease evidence before program review.
Polycomb protein EED
Review this target as Polycomb protein EED, mapped to UniProt O75530. Sequence length is 441 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Polycomb protein EED as ChEMBL target CHEMBL2189117, mapped to UniProt O75530. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Polycomb protein EED is the right protein anchor across sources, using UniProt O75530 as the stable mapping.
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| Preferred Name | Polycomb protein EED |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O75530 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Polycomb protein EED |
| UniProt Accession | O75530 |
| Component Type | Protein |
| Sequence Length | 441 aa |
Polycomb protein EED
Review this target as Polycomb protein EED, mapped to UniProt O75530. Sequence length is 441 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4637096 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL4637520 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL4870920 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL4755687 | 9.61 | Kd | 0.2455 | Preclinical |
| CHEMBL4060827 | 9.54 | Ki | 0.29 | Preclinical |
| CHEMBL4084398 | 9.52 | Ki | 0.3 | Preclinical |
| CHEMBL4093096 | 9.52 | Ki | 0.3 | Preclinical |
| CHEMBL4104741 | 9.52 | Ki | 0.3 | Preclinical |
| CHEMBL4638412 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL5181703 | 9.52 | Ki | 0.3 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 69 | 443 | 7.7 |
| assay format | 29 | 326 | 7.1 |
| cell-based format | 20 | 82 | 6.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 1 | 7.0 |
| assay format | 1 | 1 | 9.4 |
| organism-based format | 1 | 0 | — |