Monoacylglycerol lipase ABHD6 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9BV23. Use UniProt Q9BV23 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9BV23 as the stable identity anchor, then attach disease evidence before program review.
Monoacylglycerol lipase ABHD6
Review this target as Monoacylglycerol lipase ABHD6, mapped to UniProt Q9BV23. Sequence length is 337 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Monoacylglycerol lipase ABHD6 as ChEMBL target CHEMBL2189127, mapped to UniProt Q9BV23. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Monoacylglycerol lipase ABHD6 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9BV23 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Monoacylglycerol lipase ABHD6 |
| UniProt Accession | Q9BV23 |
| Component Type | Protein |
| Sequence Length | 337 aa |
Monoacylglycerol lipase ABHD6
Review this target as Monoacylglycerol lipase ABHD6, mapped to UniProt Q9BV23. Sequence length is 337 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3263579 | 9.68 | IC50 | 0.21 | Preclinical |
| CHEMBL5274434 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3895863 | 8.6 | IC50 | 2.512 | Preclinical |
| CHEMBL3906477 | 8.6 | IC50 | 2.5 | Preclinical |
| CHEMBL4279328 | 8.6 | IC50 | 2.5 | Preclinical |
| CHEMBL4279884 | 8.5 | IC50 | 3.162 | Preclinical |
| CHEMBL4287766 | 8.5 | IC50 | 3.162 | Preclinical |
| CHEMBL4581240 | 8.44 | IC50 | 3.6 | Preclinical |
| CHEMBL4289572 | 8.3 | IC50 | 5.012 | Preclinical |
| CHEMBL4284689 | 8.2 | IC50 | 6.31 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 36 | 41 | 6.7 |
| single protein format | 9 | 80 | 7.1 |
| subcellular format | 1 | 32 | 6.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 1 | 1 | 8.9 |
| cell-based format | 1 | 1 | 9.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 0 | — |