Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt Q9JHG7. Use UniProt Q9JHG7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9JHG7 as the stable identity anchor, then attach disease evidence before program review.
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Review this target as Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, mapped to UniProt Q9JHG7. Sequence length is 1102 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform as ChEMBL target CHEMBL2189158, mapped to UniProt Q9JHG7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q9JHG7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
| UniProt Accession | Q9JHG7 |
| Component Type | Protein |
| Sequence Length | 1102 aa |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Review this target as Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, mapped to UniProt Q9JHG7. Sequence length is 1102 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4558527 | 9.1 | IC50 | 0.7943 | Clinical |
| CHEMBL5071394 | 9.1 | IC50 | 0.7943 | Preclinical |
| CHEMBL5091438 | 9.1 | IC50 | 0.7943 | Preclinical |
| CHEMBL5090799 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5076543 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5077865 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5086461 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5088310 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5088457 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5089084 | 9.0 | IC50 | 1.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 22 | 74 | 6.3 |
| assay format | 1 | 0 | — |
| single protein format | 1 | 0 | — |
| tissue-based format | 1 | 27 | 8.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 1 | 5.9 |