Protein kinase C alpha type · SINGLE PROTEIN · Bos taurus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P04409. Use UniProt P04409 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P04409 as the stable identity anchor, then attach disease evidence before program review.
Protein kinase C alpha type
Review this target as Protein kinase C alpha type, mapped to UniProt P04409. Sequence length is 672 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein kinase C alpha type as ChEMBL target CHEMBL2213, mapped to UniProt P04409. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Protein kinase C alpha type is the right protein anchor across sources, using UniProt P04409 as the stable mapping.
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| Preferred Name | Protein kinase C alpha type |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P04409 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein kinase C alpha type |
| UniProt Accession | P04409 |
| Component Type | Protein |
| Sequence Length | 672 aa |
Protein kinase C alpha type
Review this target as Protein kinase C alpha type, mapped to UniProt P04409. Sequence length is 672 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL27768 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL334853 | 8.74 | Ki | 1.82 | Preclinical |
| CHEMBL132720 | 8.62 | Ki | 2.39 | Preclinical |
| CHEMBL337834 | 8.44 | Ki | 3.67 | Preclinical |
| CHEMBL170518 | 8.32 | Ki | 4.8 | Preclinical |
| CHEMBL133853 | 8.25 | Ki | 5.63 | Preclinical |
| CHEMBL7463 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL294422 | 7.61 | Ki | 24.6 | Preclinical |
| CHEMBL289230 | 7.54 | Ki | 28.6 | Preclinical |
| CHEMBL38644 | 7.51 | Ki | 31.1 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 41 | 7.0 |
| assay format | 1 | 6 | 6.0 |
| cell-based format | 1 | 1 | 7.7 |