Carnitine O-palmitoyltransferase 1, muscle isoform · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q92523. Use UniProt Q92523 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q92523 as the stable identity anchor, then attach disease evidence before program review.
Carnitine O-palmitoyltransferase 1, muscle isoform
Review this target as Carnitine O-palmitoyltransferase 1, muscle isoform, mapped to UniProt Q92523. Sequence length is 772 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Carnitine O-palmitoyltransferase 1, muscle isoform as ChEMBL target CHEMBL2216739, mapped to UniProt Q92523. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Carnitine O-palmitoyltransferase 1, muscle isoform |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q92523 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Carnitine O-palmitoyltransferase 1, muscle isoform |
| UniProt Accession | Q92523 |
| Component Type | Protein |
| Sequence Length | 772 aa |
Carnitine O-palmitoyltransferase 1, muscle isoform
Review this target as Carnitine O-palmitoyltransferase 1, muscle isoform, mapped to UniProt Q92523. Sequence length is 772 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2216778 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL2216779 | 7.68 | IC50 | 21.0 | Preclinical |
| CHEMBL3431544 | 6.87 | IC50 | 133.95 | Preclinical |
| CHEMBL3431722 | 6.84 | IC50 | 145.3 | Preclinical |
| CHEMBL2216771 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL3431461 | 6.7 | IC50 | 202.0 | Preclinical |
| CHEMBL3431514 | 6.65 | IC50 | 226.05 | Preclinical |
| CHEMBL3431634 | 6.63 | IC50 | 235.3 | Preclinical |
| CHEMBL3431771 | 6.59 | IC50 | 259.2 | Preclinical |
| CHEMBL2216769 | 6.44 | IC50 | 360.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 247 | 5.3 |
| cell-based format | 1 | 3 | 6.8 |
| mitochondrion format | 1 | 1 | — |