Opioid receptors; mu and delta · PROTEIN FAMILY · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P42866. Use UniProt P42866 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P42866 as the stable identity anchor, then attach disease evidence before program review.
Mu-type opioid receptor
Review this target as Opioid receptors; mu and delta, mapped to UniProt P42866. ChEMBL maps the protein component as Mu-type opioid receptor. Sequence length is 398 aa.
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This review treats Opioid receptors; mu and delta as ChEMBL target CHEMBL2221343, mapped to UniProt P42866. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Opioid receptors; mu and delta |
| Target Type | PROTEIN FAMILY |
| Organism | Mus musculus |
| UniProt | P42866 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mu-type opioid receptor |
| UniProt Accession | P42866 |
| Component Type | Protein |
| Sequence Length | 398 aa |
Mu-type opioid receptor
Review this target as Opioid receptors; mu and delta, mapped to UniProt P42866. ChEMBL maps the protein component as Mu-type opioid receptor. Sequence length is 398 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4795492 | 10.5 | EC50 | 0.03162 | Preclinical |
| CHEMBL2151734 | 9.54 | EC50 | 0.287 | Preclinical |
| CHEMBL19019 | 9.06 | Ki | 0.871 | Approved |
| CHEMBL2151735 | 8.89 | EC50 | 1.3 | Preclinical |
| CHEMBL20226 | 8.75 | EC50 | 1.778 | Preclinical |
| CHEMBL2151245 | 8.6 | Ki | 2.512 | Preclinical |
| CHEMBL38874 | 8.57 | EC50 | 2.69 | Preclinical |
| CHEMBL1237164 | 8.46 | Ki | 3.467 | Preclinical |
| CHEMBL2151247 | 8.38 | Ki | 4.169 | Preclinical |
| CHEMBL963 | 8.33 | Ki | 4.677 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 4 | 4 | 6.2 |
| cell membrane format | 2 | 3 | 9.3 |
| assay format | 1 | 4 | 8.1 |
| organism-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 10 | 7.6 |
| protein format | 1 | 0 | — |