4-hydroxyphenylpyruvate dioxygenase · SINGLE PROTEIN · Arabidopsis thaliana
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As of 2026-09-14Protein identity stays anchored to UniProt P93836. Use UniProt P93836 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P93836 as the stable identity anchor, then attach disease evidence before program review.
4-hydroxyphenylpyruvate dioxygenase
Review this target as 4-hydroxyphenylpyruvate dioxygenase, mapped to UniProt P93836. Sequence length is 445 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 4-hydroxyphenylpyruvate dioxygenase as ChEMBL target CHEMBL2242740, mapped to UniProt P93836. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether 4-hydroxyphenylpyruvate dioxygenase is the right protein anchor across sources, using UniProt P93836 as the stable mapping.
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| Preferred Name | 4-hydroxyphenylpyruvate dioxygenase |
| Target Type | SINGLE PROTEIN |
| Organism | Arabidopsis thaliana |
| UniProt | P93836 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 4-hydroxyphenylpyruvate dioxygenase |
| UniProt Accession | P93836 |
| Component Type | Protein |
| Sequence Length | 445 aa |
4-hydroxyphenylpyruvate dioxygenase
Review this target as 4-hydroxyphenylpyruvate dioxygenase, mapped to UniProt P93836. Sequence length is 445 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4102251 | 8.3 | Ki | 5.0 | Preclinical |
| CHEMBL1230604 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL4060588 | 8.15 | Ki | 7.0 | Preclinical |
| CHEMBL4061385 | 8.15 | Ki | 7.0 | Preclinical |
| CHEMBL4069617 | 8.15 | Ki | 7.0 | Preclinical |
| CHEMBL4071950 | 8.15 | Ki | 7.0 | Preclinical |
| CHEMBL4080249 | 8.15 | Ki | 7.0 | Preclinical |
| CHEMBL4093474 | 8.15 | Ki | 7.0 | Preclinical |
| CHEMBL1230467 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL1873440 | 7.89 | Ki | 13.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 5 | 20 | 7.4 |
| single protein format | 4 | 12 | 6.5 |
| cell-based format | 2 | 1 | 6.1 |