Use UniProt A6HIV9 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2269 Target Snapshot
Retinoic acid receptor alpha · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt A6HIV9. Use UniProt A6HIV9 as the stable identity anchor, then attach disease evidence before program review.
Retinoic acid receptor, alpha
Review this target as Retinoic acid receptor alpha, mapped to UniProt A6HIV9. ChEMBL maps the protein component as Retinoic acid receptor, alpha. Sequence length is 459 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Retinoic acid receptor alpha as ChEMBL target CHEMBL2269, mapped to UniProt A6HIV9. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Retinoic acid receptor alpha |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | A6HIV9 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Retinoic acid receptor, alpha |
| UniProt Accession | A6HIV9 |
| Component Type | Protein |
| Sequence Length | 459 aa |
Retinoic acid receptor, alpha
How to read this target
Review this target as Retinoic acid receptor alpha, mapped to UniProt A6HIV9. ChEMBL maps the protein component as Retinoic acid receptor, alpha. Sequence length is 459 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL133176 | 5.85 | Ki | 1399.0 | Preclinical |
| CHEMBL336086 | 5.61 | Ki | 2481.0 | Preclinical |
| CHEMBL340555 | 5.59 | Ki | 2569.0 | Preclinical |
| CHEMBL42314 | 5.56 | Ki | 2745.0 | Preclinical |
| CHEMBL131561 | 5.47 | Ki | 3410.0 | Preclinical |
| CHEMBL132488 | 5.46 | Ki | 3442.0 | Preclinical |
| CHEMBL335751 | 5.43 | Ki | 3671.0 | Preclinical |
| CHEMBL340074 | 5.43 | Ki | 3726.0 | Preclinical |
| CHEMBL335762 | 5.27 | Ki | 5409.0 | Preclinical |
| CHEMBL129887 | 5.25 | Ki | 5650.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 1 assays, 12 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 12 | 5.4 |