Prostaglandin D2 receptor 2 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt Q9Z2J6. Use UniProt Q9Z2J6 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9Z2J6 as the stable identity anchor, then attach disease evidence before program review.
Prostaglandin D2 receptor 2
Review this target as Prostaglandin D2 receptor 2, mapped to UniProt Q9Z2J6. Sequence length is 382 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Prostaglandin D2 receptor 2 as ChEMBL target CHEMBL2291, mapped to UniProt Q9Z2J6. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Prostaglandin D2 receptor 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q9Z2J6 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Prostaglandin D2 receptor 2 |
| UniProt Accession | Q9Z2J6 |
| Component Type | Protein |
| Sequence Length | 382 aa |
Prostaglandin D2 receptor 2
Review this target as Prostaglandin D2 receptor 2, mapped to UniProt Q9Z2J6. Sequence length is 382 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1917592 | 9.43 | Ki | 0.37 | Preclinical |
| CHEMBL1778639 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL1917584 | 8.62 | Ki | 2.4 | Preclinical |
| CHEMBL217053 | 8.49 | IC50 | 3.2 | Preclinical |
| CHEMBL1088284 | 8.47 | IC50 | 3.4 | Preclinical |
| CHEMBL3236948 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL260672 | 8.3 | Ki | 5.0 | Preclinical |
| CHEMBL2204469 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL2442750 | 8.0 | Ki | 10.0 | Clinical |
| CHEMBL260674 | 7.66 | Ki | 22.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 5 | 8.5 |
| cell-based format | 4 | 11 | 7.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 2 | 6.9 |