Use UniProt A4IFJ5 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2304401 Target Snapshot
Cytosolic phospholipase A2 · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt A4IFJ5. Use UniProt A4IFJ5 as the stable identity anchor, then attach disease evidence before program review.
Cytosolic phospholipase A2
Review this target as Cytosolic phospholipase A2, mapped to UniProt A4IFJ5. Sequence length is 749 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Cytosolic phospholipase A2 as ChEMBL target CHEMBL2304401, mapped to UniProt A4IFJ5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cytosolic phospholipase A2 |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | A4IFJ5 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cytosolic phospholipase A2 |
| UniProt Accession | A4IFJ5 |
| Component Type | Protein |
| Sequence Length | 749 aa |
Cytosolic phospholipase A2
How to read this target
Review this target as Cytosolic phospholipase A2, mapped to UniProt A4IFJ5. Sequence length is 749 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL87987 | 6.3 | IC50 | 500.0 | Preclinical |
| CHEMBL90083 | 5.85 | IC50 | 1400.0 | Preclinical |
| CHEMBL91419 | 5.85 | IC50 | 1400.0 | Preclinical |
| CHEMBL312824 | 5.8 | IC50 | 1600.0 | Preclinical |
| CHEMBL313460 | 5.8 | IC50 | 1600.0 | Preclinical |
| CHEMBL91323 | 5.8 | IC50 | 1600.0 | Preclinical |
| CHEMBL91502 | 5.8 | IC50 | 1600.0 | Preclinical |
| CHEMBL90297 | 5.72 | IC50 | 1900.0 | Preclinical |
| CHEMBL89888 | 5.52 | IC50 | 3000.0 | Preclinical |
| CHEMBL115454 | 5.48 | IC50 | 3300.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Functional — 3 assays, 63 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 3 | 63 | 5.2 |