Adenosine receptor A1 · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-13Protein identity stays anchored to UniProt P47745. Use UniProt P47745 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P47745 as the stable identity anchor, then attach disease evidence before program review.
Adenosine receptor A1
Review this target as Adenosine receptor A1, mapped to UniProt P47745. Sequence length is 326 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Adenosine receptor A1 as ChEMBL target CHEMBL2304404, mapped to UniProt P47745. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Adenosine receptor A1 |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | P47745 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Adenosine receptor A1 |
| UniProt Accession | P47745 |
| Component Type | Protein |
| Sequence Length | 326 aa |
Adenosine receptor A1
Review this target as Adenosine receptor A1, mapped to UniProt P47745. Sequence length is 326 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL489640 | 9.49 | Ki | 0.32 | Preclinical |
| CHEMBL68738 | 9.49 | Ki | 0.32 | Preclinical |
| CHEMBL61845 | 9.25 | IC50 | 0.56 | Preclinical |
| CHEMBL440115 | 9.25 | IC50 | 0.56 | Preclinical |
| CHEMBL604242 | 9.12 | Ki | 0.75 | Preclinical |
| CHEMBL605856 | 9.12 | Ki | 0.75 | Preclinical |
| CHEMBL605440 | 9.12 | Ki | 0.75 | Preclinical |
| CHEMBL2093942 | 9.1 | Ki | 0.8 | Preclinical |
| CHEMBL464859 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL284969 | 9.0 | Ki | 1.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 51 | 52 | 7.0 |
| cell membrane format | 13 | 118 | 6.8 |
| single protein format | 4 | 28 | 5.5 |
| tissue-based format | 3 | 47 | 5.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 9 | 98 | 5.1 |
| tissue-based format | 2 | 0 | — |