Receptor tyrosine-protein kinase erbB-2 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P70424. Use UniProt P70424 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P70424 as the stable identity anchor, then attach disease evidence before program review.
Receptor tyrosine-protein kinase erbB-2
Review this target as Receptor tyrosine-protein kinase erbB-2, mapped to UniProt P70424. Sequence length is 1256 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Receptor tyrosine-protein kinase erbB-2 as ChEMBL target CHEMBL2311234, mapped to UniProt P70424. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Receptor tyrosine-protein kinase erbB-2 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P70424 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Receptor tyrosine-protein kinase erbB-2 |
| UniProt Accession | P70424 |
| Component Type | Protein |
| Sequence Length | 1256 aa |
Receptor tyrosine-protein kinase erbB-2
Review this target as Receptor tyrosine-protein kinase erbB-2, mapped to UniProt P70424. Sequence length is 1256 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL545315 | 7.8 | IC50 | 16.0 | Clinical |
| CHEMBL2110732 | 7.39 | IC50 | 41.0 | Approved |
| CHEMBL553 | 6.52 | IC50 | 299.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 3 | 7.2 |