Laforin · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt O95278. Use UniProt O95278 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O95278 as the stable identity anchor, then attach disease evidence before program review.
Laforin
Review this target as Laforin, mapped to UniProt O95278. Sequence length is 331 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Laforin as ChEMBL target CHEMBL2311242, mapped to UniProt O95278. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Laforin is the right protein anchor across sources, using UniProt O95278 as the stable mapping.
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| Preferred Name | Laforin |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O95278 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Laforin |
| UniProt Accession | O95278 |
| Component Type | Protein |
| Sequence Length | 331 aa |
Laforin
Review this target as Laforin, mapped to UniProt O95278. Sequence length is 331 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3426913 | 4.99 | IC50 | 10300.0 | Preclinical |
| CHEMBL5567968 | 4.94 | IC50 | 11410.0 | Preclinical |
| CHEMBL3319356 | 4.91 | IC50 | 12200.0 | Preclinical |
| CHEMBL2316907 | 4.51 | IC50 | 31000.0 | Preclinical |
| CHEMBL2316902 | 4.4 | IC50 | 40000.0 | Preclinical |
| CHEMBL3596431 | 4.25 | IC50 | 56000.0 | Preclinical |
| CHEMBL5560087 | 4.22 | IC50 | 59700.0 | Preclinical |
| CHEMBL5568311 | 4.21 | IC50 | 61300.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 6 | 3 | 4.7 |
| assay format | 2 | 10 | 4.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |