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Target Snapshot

CHEMBL2314 Target Snapshot

L-xylulose reductase · SINGLE PROTEIN · Homo sapiens

12Compounds
3Assays
0Approved Drugs
1.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt Q7Z4W1. Use UniProt Q7Z4W1 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q7Z4W1 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats L-xylulose reductase as ChEMBL target CHEMBL2314, mapped to UniProt Q7Z4W1. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
L-xylulose reductase
SINGLE PROTEIN · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL2314
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
Q7Z4W1
L-xylulose reductase
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether L-xylulose reductase is the right protein anchor across sources, using UniProt Q7Z4W1 as the stable mapping.

Jump to Protein Context
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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelL-xylulose reductase
UniProt AccessionQ7Z4W1
Component TypeProtein
Sequence Length244 aa

L-xylulose reductase

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as L-xylulose reductase, mapped to UniProt Q7Z4W1. Sequence length is 244 aa.

Mapped IDQ7Z4W1
Review nameL-xylulose reductase
OrganismHomo sapiens
Assay Mix

Activity Type Distribution

KD1.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5653589 9.02 Kd 0.963 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
1
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

3
Total Assays
1
Tested Compounds
1
Assay Types
Binding — 3 assays, 1 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 3 1 9.0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine