Potassium channel subfamily K member 9 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Potassium channel subfamily K member 9 shows approved-linked disease relevance led by lung disease. 5 more disease programs remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Protein identity stays anchored to UniProt Q9NPC2. Start with lung disease, then reuse UniProt Q9NPC2 as the stable protein anchor across project notes and exports.
Start with lung disease, then reuse UniProt Q9NPC2 as the stable protein anchor across project notes and exports.
Potassium channel subfamily K member 9 shows approved-linked disease relevance led by lung disease. 5 more disease programs remain visible in the same review block. 1 linked drug remains visible in the same block.
Start review with lung disease because it currently carries approved-linked support. Linked drugs include DOXAPRAM HYDROCHLORIDE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyPotassium channel subfamily K member 9
Review this target as Potassium channel subfamily K member 9, mapped to UniProt Q9NPC2. Sequence length is 374 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Potassium channel subfamily K member 9 as ChEMBL target CHEMBL2321614, mapped to UniProt Q9NPC2. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
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Start here when your first question is whether Potassium channel subfamily K member 9 is the right protein anchor across sources, using UniProt Q9NPC2 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why lung disease is currently framed as approved-linked support. It currently carries 1 linked drug in the same disease frame.
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| Preferred Name | Potassium channel subfamily K member 9 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9NPC2 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Potassium channel subfamily K member 9 |
| UniProt Accession | Q9NPC2 |
| Component Type | Protein |
| Sequence Length | 374 aa |
Potassium channel subfamily K member 9
Review this target as Potassium channel subfamily K member 9, mapped to UniProt Q9NPC2. Sequence length is 374 aa.
Open Targets-ready disease context using the current target-indication evidence contract.
Potassium channel subfamily K member 9 shows approved-linked disease relevance led by lung disease. 5 more disease programs remain visible in the same review block.
Start review with lung disease because it currently carries approved-linked support. Linked drugs include DOXAPRAM HYDROCHLORIDE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL6016320 | 8.98 | IC50 | 1.04 | Preclinical |
| CHEMBL5925518 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL5797600 | 8.85 | IC50 | 1.4 | Preclinical |
| CHEMBL5757092 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL5971519 | 8.8 | IC50 | 1.6 | Preclinical |
| CHEMBL5095055 | 8.74 | IC50 | 1.8 | Clinical |
| CHEMBL5885911 | 8.66 | IC50 | 2.2 | Preclinical |
| CHEMBL5979320 | 8.64 | IC50 | 2.3 | Preclinical |
| CHEMBL5886272 | 8.55 | IC50 | 2.8 | Preclinical |
| CHEMBL5856031 | 8.52 | IC50 | 3.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 29 | 349 | 6.7 |
| single protein format | 2 | 1 | 7.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 0 | — |