Ubiquitin-like modifier-activating enzyme ATG7 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O95352. Use UniProt O95352 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O95352 as the stable identity anchor, then attach disease evidence before program review.
Ubiquitin-like modifier-activating enzyme ATG7
Review this target as Ubiquitin-like modifier-activating enzyme ATG7, mapped to UniProt O95352. Sequence length is 703 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ubiquitin-like modifier-activating enzyme ATG7 as ChEMBL target CHEMBL2321621, mapped to UniProt O95352. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Ubiquitin-like modifier-activating enzyme ATG7 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O95352 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ubiquitin-like modifier-activating enzyme ATG7 |
| UniProt Accession | O95352 |
| Component Type | Protein |
| Sequence Length | 703 aa |
Ubiquitin-like modifier-activating enzyme ATG7
Review this target as Ubiquitin-like modifier-activating enzyme ATG7, mapped to UniProt O95352. Sequence length is 703 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4577235 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL4464238 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL4554226 | 7.77 | IC50 | 17.0 | Preclinical |
| CHEMBL4543856 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL4434940 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL4436997 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL4439106 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL4444895 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL4447381 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL4449596 | 7.7 | IC50 | 20.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 9 | 205 | 7.2 |
| cell-based format | 3 | 26 | 6.5 |