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Target Snapshot

CHEMBL2321641 Target Snapshot

Steroid Delta-isomerase · SINGLE PROTEIN · Pseudomonas putida

6Compounds
3Assays
1Approved Drugs
7.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P07445. Use UniProt P07445 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P07445 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Steroid Delta-isomerase as ChEMBL target CHEMBL2321641, mapped to UniProt P07445. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Steroid Delta-isomerase
SINGLE PROTEIN · Pseudomonas putida
As of 2026-09-14
ChEMBL target ID
CHEMBL2321641
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P07445
Steroid Delta-isomerase
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Steroid Delta-isomerase is the right protein anchor across sources, using UniProt P07445 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSteroid Delta-isomerase
UniProt AccessionP07445
Component TypeProtein
Sequence Length131 aa

Steroid Delta-isomerase

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Steroid Delta-isomerase, mapped to UniProt P07445. Sequence length is 131 aa.

Mapped IDP07445
Review nameSteroid Delta-isomerase
OrganismPseudomonas putida
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

KD7.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL406393 4.8 Kd 16000.0 Approved
CHEMBL1499599 4.66 Kd 22000.0 Preclinical
CHEMBL1338939 4.34 Kd 46000.0 Preclinical
CHEMBL107281 4.3 Kd 50000.0 Preclinical
CHEMBL382602 4.2 Kd 63000.0 Preclinical
CHEMBL2322559 3.75 Kd 180000.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

3
Total Assays
6
Tested Compounds
1
Assay Types
Binding — 3 assays, 6 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 3 6 4.4

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine