Histone-lysine N-methyltransferase KMT5C · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q86Y97. Use UniProt Q86Y97 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q86Y97 as the stable identity anchor, then attach disease evidence before program review.
Histone-lysine N-methyltransferase KMT5C
Review this target as Histone-lysine N-methyltransferase KMT5C, mapped to UniProt Q86Y97. Sequence length is 462 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Histone-lysine N-methyltransferase KMT5C as ChEMBL target CHEMBL2321644, mapped to UniProt Q86Y97. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Histone-lysine N-methyltransferase KMT5C is the right protein anchor across sources, using UniProt Q86Y97 as the stable mapping.
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| Preferred Name | Histone-lysine N-methyltransferase KMT5C |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q86Y97 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Histone-lysine N-methyltransferase KMT5C |
| UniProt Accession | Q86Y97 |
| Component Type | Protein |
| Sequence Length | 462 aa |
Histone-lysine N-methyltransferase KMT5C
Review this target as Histone-lysine N-methyltransferase KMT5C, mapped to UniProt Q86Y97. Sequence length is 462 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4521971 | 6.84 | IC50 | 144.0 | Preclinical |
| CHEMBL4521971 | 6.58 | EC50 | 262.0 | Preclinical |
| CHEMBL5653590 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL1288796 | 5.32 | IC50 | 4800.0 | Preclinical |
| CHEMBL418052 | 5.0 | IC50 | 10000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 42 | 4 | 6.1 |
| cell-based format | 3 | 1 | 6.6 |