Cathepsin B · SINGLE PROTEIN · Bos taurus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P07688. Use UniProt P07688 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P07688 as the stable identity anchor, then attach disease evidence before program review.
Cathepsin B
Review this target as Cathepsin B, mapped to UniProt P07688. Sequence length is 335 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cathepsin B as ChEMBL target CHEMBL2323, mapped to UniProt P07688. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Cathepsin B is the right protein anchor across sources, using UniProt P07688 as the stable mapping.
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| Preferred Name | Cathepsin B |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P07688 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cathepsin B |
| UniProt Accession | P07688 |
| Component Type | Protein |
| Sequence Length | 335 aa |
Cathepsin B
Review this target as Cathepsin B, mapped to UniProt P07688. Sequence length is 335 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2373045 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL131540 | 7.51 | Ki | 31.0 | Preclinical |
| CHEMBL2373041 | 7.41 | IC50 | 39.0 | Preclinical |
| CHEMBL51128 | 7.4 | Ki | 40.0 | Preclinical |
| CHEMBL132987 | 7.2 | Ki | 63.0 | Preclinical |
| CHEMBL421910 | 7.2 | Ki | 63.0 | Preclinical |
| CHEMBL130122 | 7.14 | Ki | 72.0 | Preclinical |
| CHEMBL3706739 | 7.03 | Ki | 94.0 | Preclinical |
| CHEMBL131707 | 7.02 | Ki | 96.0 | Preclinical |
| CHEMBL131639 | 7.0 | Ki | 100.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 32 | 121 | 5.8 |
| tissue-based format | 5 | 0 | — |
| assay format | 1 | 0 | — |