Phenylethanolamine N-methyltransferase · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt P10938. Use UniProt P10938 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P10938 as the stable identity anchor, then attach disease evidence before program review.
Phenylethanolamine N-methyltransferase
Review this target as Phenylethanolamine N-methyltransferase, mapped to UniProt P10938. Sequence length is 283 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Phenylethanolamine N-methyltransferase as ChEMBL target CHEMBL2331, mapped to UniProt P10938. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Phenylethanolamine N-methyltransferase |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P10938 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phenylethanolamine N-methyltransferase |
| UniProt Accession | P10938 |
| Component Type | Protein |
| Sequence Length | 283 aa |
Phenylethanolamine N-methyltransferase
Review this target as Phenylethanolamine N-methyltransferase, mapped to UniProt P10938. Sequence length is 283 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL287837 | 8.51 | Ki | 3.1 | Preclinical |
| CHEMBL541538 | 8.1 | Ki | 8.0 | Preclinical |
| CHEMBL281864 | 7.25 | Ki | 56.0 | Preclinical |
| CHEMBL357424 | 7.17 | Ki | 67.0 | Preclinical |
| CHEMBL59719 | 7.14 | Ki | 72.0 | Preclinical |
| CHEMBL281289 | 6.92 | Ki | 120.0 | Preclinical |
| CHEMBL27499 | 6.75 | Ki | 180.0 | Preclinical |
| CHEMBL275595 | 6.68 | Ki | 210.0 | Preclinical |
| CHEMBL38681 | 6.66 | Ki | 220.0 | Preclinical |
| CHEMBL293700 | 6.62 | Ki | 240.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 70 | 296 | 5.5 |
| tissue-based format | 3 | 16 | 4.4 |
| organism-based format | 1 | 0 | — |