Vascular endothelial growth factor receptor 2 · SINGLE PROTEIN · Danio rerio
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As of 2026-09-14Protein identity stays anchored to UniProt Q5GIT4. Use UniProt Q5GIT4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q5GIT4 as the stable identity anchor, then attach disease evidence before program review.
Vascular endothelial growth factor receptor 2
Review this target as Vascular endothelial growth factor receptor 2, mapped to UniProt Q5GIT4. Sequence length is 1357 aa.
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This review treats Vascular endothelial growth factor receptor 2 as ChEMBL target CHEMBL2331049, mapped to UniProt Q5GIT4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Vascular endothelial growth factor receptor 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Danio rerio |
| UniProt | Q5GIT4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Vascular endothelial growth factor receptor 2 |
| UniProt Accession | Q5GIT4 |
| Component Type | Protein |
| Sequence Length | 1357 aa |
Vascular endothelial growth factor receptor 2
Review this target as Vascular endothelial growth factor receptor 2, mapped to UniProt Q5GIT4. Sequence length is 1357 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2331570 | 5.98 | IC50 | 1050.0 | Preclinical |
| CHEMBL2332849 | 5.92 | IC50 | 1200.0 | Preclinical |
| CHEMBL2332840 | 5.65 | IC50 | 2250.0 | Preclinical |
| CHEMBL1336 | 5.58 | IC50 | 2600.0 | Approved |
| CHEMBL2332870 | 5.29 | IC50 | 5180.0 | Preclinical |
| CHEMBL2332867 | 5.11 | IC50 | 7730.0 | Preclinical |
| CHEMBL2332871 | 5.07 | IC50 | 8460.0 | Preclinical |
| CHEMBL2332868 | 4.78 | IC50 | 16600.0 | Preclinical |
| CHEMBL2332869 | 4.75 | IC50 | 17760.0 | Preclinical |
| CHEMBL2332860 | 4.69 | IC50 | 20230.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 23 | 0 | — |
| single protein format | 8 | 16 | 4.8 |
| assay format | 2 | 0 | — |