Delta(24)-sterol reductase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q15392. Use UniProt Q15392 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q15392 as the stable identity anchor, then attach disease evidence before program review.
Delta(24)-sterol reductase
Review this target as Delta(24)-sterol reductase, mapped to UniProt Q15392. Sequence length is 516 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Delta(24)-sterol reductase as ChEMBL target CHEMBL2331059, mapped to UniProt Q15392. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Delta(24)-sterol reductase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q15392 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Delta(24)-sterol reductase |
| UniProt Accession | Q15392 |
| Component Type | Protein |
| Sequence Length | 516 aa |
Delta(24)-sterol reductase
Review this target as Delta(24)-sterol reductase, mapped to UniProt Q15392. Sequence length is 516 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4164183 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL352837 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL4174848 | 8.6 | IC50 | 2.5 | Preclinical |
| CHEMBL4170755 | 8.54 | IC50 | 2.9 | Preclinical |
| CHEMBL4164005 | 8.48 | IC50 | 3.3 | Preclinical |
| CHEMBL4167637 | 8.38 | IC50 | 4.2 | Preclinical |
| CHEMBL4159728 | 8.26 | IC50 | 5.5 | Preclinical |
| CHEMBL4164428 | 8.2 | IC50 | 6.3 | Preclinical |
| CHEMBL4167452 | 6.7 | IC50 | 198.0 | Preclinical |
| CHEMBL4172305 | 6.69 | IC50 | 203.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 13 | 7.7 |
| single protein format | 3 | 1 | 4.4 |
| subcellular format | 2 | 1 | 6.4 |