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Target Snapshot

CHEMBL2344 Target Snapshot

Vasopressin V2 receptor · SINGLE PROTEIN · Bos taurus

22Compounds
3Assays
1Approved Drugs
32.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P48044. Use UniProt P48044 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P48044 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Vasopressin V2 receptor as ChEMBL target CHEMBL2344, mapped to UniProt P48044. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Vasopressin V2 receptor
SINGLE PROTEIN · Bos taurus
As of 2026-09-14
ChEMBL target ID
CHEMBL2344
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P48044
Vasopressin V2 receptor
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Vasopressin V2 receptor is the right protein anchor across sources, using UniProt P48044 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelVasopressin V2 receptor
UniProt AccessionP48044
Component TypeProtein
Sequence Length370 aa

Vasopressin V2 receptor

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Vasopressin V2 receptor, mapped to UniProt P48044. Sequence length is 370 aa.

Mapped IDP48044
Review nameVasopressin V2 receptor
OrganismBos taurus
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

KD32.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL406303 8.85 Kd 1.4 Preclinical
CHEMBL373742 8.82 Kd 1.5 Approved
CHEMBL413249 8.06 Kd 8.7 Preclinical
CHEMBL217517 8.03 Kd 9.4 Preclinical
CHEMBL2371674 8.03 Kd 9.4 Preclinical
CHEMBL265119 8.0 Kd 10.0 Preclinical
CHEMBL269715 7.68 Kd 21.0 Preclinical
CHEMBL438387 7.54 Kd 29.0 Preclinical
CHEMBL437631 7.48 Kd 33.0 Preclinical
CHEMBL415230 7.46 Kd 35.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
2
6.0
6
6.5
5
7.0
2
7.5
4
8.0
2
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

VASOPRESSIN
CHEMBL373742
Approved 2014
Assay Landscape

Assay Landscape

3
Total Assays
22
Tested Compounds
1
Assay Types
Binding — 3 assays, 22 compounds
BAO Format Assays Compounds Avg pChEMBL
tissue-based format 2 10 7.8
assay format 1 12 7.0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine