Phosphorylase b kinase gamma catalytic chain, liver/testis isoform · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P15735. Use UniProt P15735 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P15735 as the stable identity anchor, then attach disease evidence before program review.
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform
Review this target as Phosphorylase b kinase gamma catalytic chain, liver/testis isoform, mapped to UniProt P15735. Sequence length is 406 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Phosphorylase b kinase gamma catalytic chain, liver/testis isoform as ChEMBL target CHEMBL2349, mapped to UniProt P15735. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P15735 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform |
| UniProt Accession | P15735 |
| Component Type | Protein |
| Sequence Length | 406 aa |
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform
Review this target as Phosphorylase b kinase gamma catalytic chain, liver/testis isoform, mapped to UniProt P15735. Sequence length is 406 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 9.85 | Kd | 0.14 | Preclinical |
| CHEMBL388978 | 9.47 | IC50 | 0.336 | Preclinical |
| CHEMBL603469 | 8.77 | Kd | 1.7 | Clinical |
| CHEMBL535 | 8.23 | Kd | 5.9 | Approved |
| CHEMBL2151321 | 8.21 | IC50 | 6.1 | Preclinical |
| CHEMBL509032 | 8.1 | Ki | 7.943 | Preclinical |
| CHEMBL2001751 | 7.9 | Ki | 12.59 | Preclinical |
| CHEMBL509032 | 7.89 | Kd | 13.0 | Preclinical |
| CHEMBL1990885 | 7.8 | Ki | 15.85 | Preclinical |
| CHEMBL5653589 | 7.75 | Kd | 17.58 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 178 | 34 | 6.8 |
| assay format | 42 | 1 | 6.7 |
| subcellular format | 24 | 20 | 5.9 |
| cell-based format | 12 | 2 | 7.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 128 | 5.9 |