Calcium/calmodulin-dependent protein kinase type II subunit alpha · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P11275. Use UniProt P11275 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P11275 as the stable identity anchor, then attach disease evidence before program review.
Calcium/calmodulin-dependent protein kinase type II subunit alpha
Review this target as Calcium/calmodulin-dependent protein kinase type II subunit alpha, mapped to UniProt P11275. Sequence length is 478 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Calcium/calmodulin-dependent protein kinase type II subunit alpha as ChEMBL target CHEMBL2359, mapped to UniProt P11275. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P11275 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| UniProt Accession | P11275 |
| Component Type | Protein |
| Sequence Length | 478 aa |
Calcium/calmodulin-dependent protein kinase type II subunit alpha
Review this target as Calcium/calmodulin-dependent protein kinase type II subunit alpha, mapped to UniProt P11275. Sequence length is 478 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL190035 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL240714 | 8.68 | IC50 | 2.1 | Preclinical |
| CHEMBL5206854 | 7.85 | Ki | 14.0 | Preclinical |
| CHEMBL1031 | 7.66 | Ki | 22.0 | Preclinical |
| CHEMBL5175277 | 7.66 | Ki | 22.0 | Preclinical |
| CHEMBL5191835 | 7.6 | Ki | 25.12 | Preclinical |
| CHEMBL5196669 | 7.51 | Ki | 31.0 | Preclinical |
| CHEMBL5176248 | 7.5 | Ki | 31.62 | Preclinical |
| CHEMBL5178954 | 7.5 | Ki | 31.62 | Preclinical |
| CHEMBL5170394 | 7.4 | Ki | 39.81 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 6 | 37 | 6.7 |
| cell-based format | 2 | 6 | 5.7 |
| single protein format | 1 | 0 | — |
| tissue-based format | 1 | 1 | 6.3 |