Thymidylate kinase · SINGLE PROTEIN · Mycobacterium tuberculosis
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As of 2026-09-14Protein identity stays anchored to UniProt P9WKE1. Use UniProt P9WKE1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P9WKE1 as the stable identity anchor, then attach disease evidence before program review.
Thymidylate kinase
Review this target as Thymidylate kinase, mapped to UniProt P9WKE1. Sequence length is 214 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Thymidylate kinase as ChEMBL target CHEMBL2361, mapped to UniProt P9WKE1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Thymidylate kinase |
| Target Type | SINGLE PROTEIN |
| Organism | Mycobacterium tuberculosis |
| UniProt | P9WKE1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Thymidylate kinase |
| UniProt Accession | P9WKE1 |
| Component Type | Protein |
| Sequence Length | 214 aa |
Thymidylate kinase
Review this target as Thymidylate kinase, mapped to UniProt P9WKE1. Sequence length is 214 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3394234 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL3394233 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3394236 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL3394163 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL3394232 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL3394237 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL3394161 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL3394162 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL3394235 | 7.77 | IC50 | 17.0 | Preclinical |
| CHEMBL3394249 | 7.66 | IC50 | 22.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 34 | 172 | 5.1 |
| assay format | 5 | 75 | 5.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 0 | — |