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Target Snapshot

CHEMBL2362972 Target Snapshot

Penicillin-binding protein · PROTEIN FAMILY · Staphylococcus aureus

0Compounds
0Assays
0Approved Drugs
0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Penicillin-binding protein shows approved-linked disease relevance led by infection. 1 more disease program remain visible in the same review block. 3 linked drugs keep the current disease frame grounded. Protein identity stays anchored to UniProt P72355. Start with infection, then reuse UniProt P72355 as the stable protein anchor across project notes and exports.

Review focus
Review-ready target frame

Start with infection, then reuse UniProt P72355 as the stable protein anchor across project notes and exports.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14 3 linked drugs
Open source guide
Disease program
infection

Penicillin-binding protein shows approved-linked disease relevance led by infection. 1 more disease program remain visible in the same review block. 3 linked drugs remain visible in the same block.

Start review with infection because it currently carries approved-linked support. Linked drugs include DICLOXACILLIN SODIUM, NAFCILLIN SODIUM, OXACILLIN SODIUM. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Disease source · ChEMBL drug mechanism + indication proxy
Approved-linked Open Targets-ready proxy 3 linked drugs
Open disease block
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Penicillin-binding protein as ChEMBL target CHEMBL2362972, mapped to UniProt P72355. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Penicillin-binding protein
PROTEIN FAMILY · Staphylococcus aureus
As of 2026-09-14
ChEMBL target ID
CHEMBL2362972
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P72355
Penicillin-binding protein 4
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Penicillin-binding protein is the right protein anchor across sources, using UniProt P72355 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need to confirm why infection is currently framed as approved-linked support. It currently carries 3 linked drugs in the same disease frame.

Jump to Disease Context
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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelPenicillin-binding protein 4
UniProt AccessionP72355
Component TypeProtein
Sequence Length431 aa

Penicillin-binding protein 4

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Penicillin-binding protein, mapped to UniProt P72355. ChEMBL maps the protein component as Penicillin-binding protein 4. Sequence length is 431 aa.

Mapped IDP72355
Review namePenicillin-binding protein
OrganismStaphylococcus aureus
Disease Relevance

Disease Relevance & Evidence Level

Open Targets-ready disease context using the current target-indication evidence contract.

Approved-linked Open Targets-ready proxy

Penicillin-binding protein shows approved-linked disease relevance led by infection. 1 more disease program remain visible in the same review block.

Approved-linked Approved
infection
3 linked drugs · 3 direct · 3 efficacy
Linked drugDICLOXACILLIN SODIUM
Linked drugNAFCILLIN SODIUM
Linked drugOXACILLIN SODIUM
Mechanism-linked
osteomyelitis
3 linked drugs · 3 direct · 3 efficacy
Linked drugDICLOXACILLIN SODIUM
Linked drugNAFCILLIN SODIUM
Linked drugOXACILLIN SODIUM
Source · ChEMBL drug mechanism + indication proxy
Review Cue

How to read disease relevance

Start review with infection because it currently carries approved-linked support. Linked drugs include DICLOXACILLIN SODIUM, NAFCILLIN SODIUM, OXACILLIN SODIUM. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Lead diseaseinfection
Strongest levelApproved-linked
Block modeOpen Targets-ready proxy
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Source · ChEMBL 36 via Core Engine