Probable global transcription activator SNF2L2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P51531. Use UniProt P51531 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P51531 as the stable identity anchor, then attach disease evidence before program review.
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
Review this target as Probable global transcription activator SNF2L2, mapped to UniProt P51531. ChEMBL maps the protein component as SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2. Sequence length is 1590 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Probable global transcription activator SNF2L2 as ChEMBL target CHEMBL2362979, mapped to UniProt P51531. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Probable global transcription activator SNF2L2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P51531 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 |
| UniProt Accession | P51531 |
| Component Type | Protein |
| Sequence Length | 1590 aa |
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
Review this target as Probable global transcription activator SNF2L2, mapped to UniProt P51531. ChEMBL maps the protein component as SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2. Sequence length is 1590 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5564941 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL5415064 | 8.7 | Kd | 2.0 | Preclinical |
| CHEMBL5571722 | 8.57 | IC50 | 2.7 | Preclinical |
| CHEMBL5412292 | 8.52 | Kd | 3.0 | Preclinical |
| CHEMBL4278436 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL5420238 | 8.0 | Kd | 10.0 | Preclinical |
| CHEMBL4294655 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL4278436 | 7.89 | Kd | 13.0 | Preclinical |
| CHEMBL5409404 | 7.89 | Kd | 13.0 | Preclinical |
| CHEMBL5308262 | 7.86 | IC50 | 13.8 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 49 | 47 | 6.6 |
| assay format | 30 | 12 | 6.0 |
| cell-based format | 23 | 14 | 6.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 2 | 6.6 |
| cell-based format | 1 | 18 | 4.8 |