Start with leprosy, then reuse UniProt P0C0X1 as the stable protein anchor across project notes and exports.
CHEMBL2362993 Target Snapshot
Dihydropteroate synthase · SINGLE PROTEIN · Mycobacterium leprae (strain TN)
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As of 2026-09-13Dihydropteroate synthase shows approved-linked disease relevance led by leprosy. 5 more disease programs remain visible in the same review block. 2 linked drugs keep the current disease frame grounded. Protein identity stays anchored to UniProt P0C0X1. Start with leprosy, then reuse UniProt P0C0X1 as the stable protein anchor across project notes and exports.
Dihydropteroate synthase shows approved-linked disease relevance led by leprosy. 5 more disease programs remain visible in the same review block. 2 linked drugs remain visible in the same block.
Start review with leprosy because it currently carries approved-linked support. Linked drugs include DAPSONE, SULFOXONE SODIUM. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyDihydropteroate synthase
Review this target as Dihydropteroate synthase, mapped to UniProt P0C0X1. Sequence length is 284 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Dihydropteroate synthase as ChEMBL target CHEMBL2362993, mapped to UniProt P0C0X1. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Start with the right source
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Start here when your first question is whether Dihydropteroate synthase is the right protein anchor across sources, using UniProt P0C0X1 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why leprosy is currently framed as approved-linked support. It currently carries 2 linked drugs in the same disease frame.
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Open Review-ready CardBasic Information
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| Preferred Name | Dihydropteroate synthase |
| Target Type | SINGLE PROTEIN |
| Organism | Mycobacterium leprae (strain TN) |
| UniProt | P0C0X1 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Dihydropteroate synthase |
| UniProt Accession | P0C0X1 |
| Component Type | Protein |
| Sequence Length | 284 aa |
Dihydropteroate synthase
How to read this target
Review this target as Dihydropteroate synthase, mapped to UniProt P0C0X1. Sequence length is 284 aa.
Disease Relevance & Evidence Level
Open Targets-ready disease context using the current target-indication evidence contract.
Dihydropteroate synthase shows approved-linked disease relevance led by leprosy. 5 more disease programs remain visible in the same review block.
How to read disease relevance
Start review with leprosy because it currently carries approved-linked support. Linked drugs include DAPSONE, SULFOXONE SODIUM. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.