Voltage-gated inwardly rectifying potassium channel KCNH3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9ULD8. Use UniProt Q9ULD8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9ULD8 as the stable identity anchor, then attach disease evidence before program review.
Voltage-gated inwardly rectifying potassium channel KCNH3
Review this target as Voltage-gated inwardly rectifying potassium channel KCNH3, mapped to UniProt Q9ULD8. Sequence length is 1083 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Voltage-gated inwardly rectifying potassium channel KCNH3 as ChEMBL target CHEMBL2363017, mapped to UniProt Q9ULD8. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Voltage-gated inwardly rectifying potassium channel KCNH3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9ULD8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Voltage-gated inwardly rectifying potassium channel KCNH3 |
| UniProt Accession | Q9ULD8 |
| Component Type | Protein |
| Sequence Length | 1083 aa |
Voltage-gated inwardly rectifying potassium channel KCNH3
Review this target as Voltage-gated inwardly rectifying potassium channel KCNH3, mapped to UniProt Q9ULD8. Sequence length is 1083 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3987187 | 7.33 | IC50 | 47.0 | Preclinical |
| CHEMBL3902034 | 7.28 | IC50 | 52.0 | Preclinical |
| CHEMBL3960526 | 7.24 | IC50 | 58.0 | Preclinical |
| CHEMBL3908982 | 7.19 | IC50 | 65.0 | Preclinical |
| CHEMBL3918973 | 7.14 | IC50 | 73.0 | Preclinical |
| CHEMBL3979641 | 7.11 | IC50 | 77.0 | Preclinical |
| CHEMBL3913727 | 7.1 | IC50 | 79.0 | Preclinical |
| CHEMBL3916475 | 7.08 | IC50 | 84.0 | Preclinical |
| CHEMBL3912592 | 7.07 | IC50 | 85.0 | Preclinical |
| CHEMBL3934480 | 7.07 | IC50 | 85.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 69 | 6.5 |
| single protein format | 1 | 1 | 4.4 |