Sphingosine 1-phosphate receptor · PROTEIN FAMILY · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Sphingosine 1-phosphate receptor shows approved-linked disease relevance led by multiple sclerosis. 5 more disease programs remain visible in the same review block. 2 linked drugs keep the current disease frame grounded. Protein identity stays anchored to UniProt Q9H228. Start with multiple sclerosis, then reuse UniProt Q9H228 as the stable protein anchor across project notes and exports.
Start with multiple sclerosis, then reuse UniProt Q9H228 as the stable protein anchor across project notes and exports.
Sphingosine 1-phosphate receptor shows approved-linked disease relevance led by multiple sclerosis. 5 more disease programs remain visible in the same review block. 2 linked drugs remain visible in the same block.
Start review with multiple sclerosis because it currently carries approved-linked support. Linked drugs include FINGOLIMOD HYDROCHLORIDE, FINGOLIMOD LAURYL SULFATE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxySphingosine 1-phosphate receptor 5
Review this target as Sphingosine 1-phosphate receptor, mapped to UniProt Q9H228. ChEMBL maps the protein component as Sphingosine 1-phosphate receptor 5. Sequence length is 398 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sphingosine 1-phosphate receptor as ChEMBL target CHEMBL2363041, mapped to UniProt Q9H228. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
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Start here when your first question is whether Sphingosine 1-phosphate receptor is the right protein anchor across sources, using UniProt Q9H228 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why multiple sclerosis is currently framed as approved-linked support. It currently carries 2 linked drugs in the same disease frame.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Sphingosine 1-phosphate receptor |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | Q9H228 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sphingosine 1-phosphate receptor 5 |
| UniProt Accession | Q9H228 |
| Component Type | Protein |
| Sequence Length | 398 aa |
Sphingosine 1-phosphate receptor 5
Review this target as Sphingosine 1-phosphate receptor, mapped to UniProt Q9H228. ChEMBL maps the protein component as Sphingosine 1-phosphate receptor 5. Sequence length is 398 aa.
Open Targets-ready disease context using the current target-indication evidence contract.
Sphingosine 1-phosphate receptor shows approved-linked disease relevance led by multiple sclerosis. 5 more disease programs remain visible in the same review block.
Start review with multiple sclerosis because it currently carries approved-linked support. Linked drugs include FINGOLIMOD HYDROCHLORIDE, FINGOLIMOD LAURYL SULFATE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.