DNA polymerase (alpha/delta/epsilon) · PROTEIN FAMILY · Homo sapiens
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As of 2026-09-14DNA polymerase (alpha/delta/epsilon) shows approved-linked disease relevance led by acute lymphoblastic leukemia. 5 more disease programs remain visible in the same review block. 4 linked drugs keep the current disease frame grounded. Protein identity stays anchored to UniProt P09884. Start with acute lymphoblastic leukemia, then reuse UniProt P09884 as the stable protein anchor across project notes and exports.
Start with acute lymphoblastic leukemia, then reuse UniProt P09884 as the stable protein anchor across project notes and exports.
DNA polymerase (alpha/delta/epsilon) shows approved-linked disease relevance led by acute lymphoblastic leukemia. 5 more disease programs remain visible in the same review block. 4 linked drugs remain visible in the same block.
Start review with acute lymphoblastic leukemia because it currently carries approved-linked support. Linked drugs include ASPACYTARABINE, CLOFARABINE, CYTARABINE, FLUDARABINE PHOSPHATE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyDNA polymerase alpha catalytic subunit
Review this target as DNA polymerase (alpha/delta/epsilon), mapped to UniProt P09884. ChEMBL maps the protein component as DNA polymerase alpha catalytic subunit. Sequence length is 1462 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats DNA polymerase (alpha/delta/epsilon) as ChEMBL target CHEMBL2363042, mapped to UniProt P09884. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether DNA polymerase (alpha/delta/epsilon) is the right protein anchor across sources, using UniProt P09884 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why acute lymphoblastic leukemia is currently framed as approved-linked support. It currently carries 4 linked drugs in the same disease frame.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | DNA polymerase (alpha/delta/epsilon) |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | P09884 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | DNA polymerase alpha catalytic subunit |
| UniProt Accession | P09884 |
| Component Type | Protein |
| Sequence Length | 1462 aa |
DNA polymerase alpha catalytic subunit
Review this target as DNA polymerase (alpha/delta/epsilon), mapped to UniProt P09884. ChEMBL maps the protein component as DNA polymerase alpha catalytic subunit. Sequence length is 1462 aa.
Open Targets-ready disease context using the current target-indication evidence contract.
DNA polymerase (alpha/delta/epsilon) shows approved-linked disease relevance led by acute lymphoblastic leukemia. 5 more disease programs remain visible in the same review block.
Start review with acute lymphoblastic leukemia because it currently carries approved-linked support. Linked drugs include ASPACYTARABINE, CLOFARABINE, CYTARABINE, FLUDARABINE PHOSPHATE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.