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Target Snapshot

CHEMBL2363046 Target Snapshot

DNA · NUCLEIC-ACID · Human immunodeficiency virus 1

0Compounds
0Assays
0Approved Drugs
0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

DNA shows approved-linked disease relevance led by HIV infection. 5 more disease programs remain visible in the same review block. 2 linked drugs keep the current disease frame grounded. Use HIV infection as the disease frame, then confirm a stable protein accession before cross-source reuse.

Review focus
Disease frame ready

Use HIV infection as the disease frame, then confirm a stable protein accession before cross-source reuse.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13 2 linked drugs
Open source guide
Disease program
HIV infection

DNA shows approved-linked disease relevance led by HIV infection. 5 more disease programs remain visible in the same review block. 2 linked drugs remain visible in the same block.

Start review with HIV infection because it currently carries approved-linked support. Linked drugs include KP-1461, LAMIVUDINE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Disease source · ChEMBL drug mechanism + indication proxy
Approved-linked Open Targets-ready proxy 2 linked drugs
Open disease block
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats DNA as ChEMBL target CHEMBL2363046. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
DNA
NUCLEIC-ACID · Human immunodeficiency virus 1
As of 2026-09-13
ChEMBL target ID
CHEMBL2363046
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether DNA still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need to confirm why HIV infection is currently framed as approved-linked support. It currently carries 2 linked drugs in the same disease frame.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelDNA
UniProt AccessionN/A

DNA

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as DNA.

Review nameDNA
OrganismHuman immunodeficiency virus 1
Disease Relevance

Disease Relevance & Evidence Level

Open Targets-ready disease context using the current target-indication evidence contract.

Approved-linked Open Targets-ready proxy

DNA shows approved-linked disease relevance led by HIV infection. 5 more disease programs remain visible in the same review block.

Approved-linked Approved
HIV infection
2 linked drugs · 2 direct · 2 efficacy
Linked drugKP-1461
Linked drugLAMIVUDINE
Approved-linked Approved
chronic hepatitis B virus infection
1 linked drug · 1 direct · 1 efficacy
Linked drugLAMIVUDINE
Approved-linked Approved
Hepatitis
1 linked drug · 1 direct · 1 efficacy
Linked drugLAMIVUDINE
Approved-linked Approved
hepatitis B virus infection
1 linked drug · 1 direct · 1 efficacy
Linked drugLAMIVUDINE
Approved-linked Approved
hepatitis B virus infection
1 linked drug · 1 direct · 1 efficacy
Linked drugLAMIVUDINE
Approved-linked Approved
HIV-1 infection
1 linked drug · 1 direct · 1 efficacy
Linked drugLAMIVUDINE
Source · ChEMBL drug mechanism + indication proxy
Review Cue

How to read disease relevance

Start review with HIV infection because it currently carries approved-linked support. Linked drugs include KP-1461, LAMIVUDINE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Lead diseaseHIV infection
Strongest levelApproved-linked
Block modeOpen Targets-ready proxy
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Source · ChEMBL 36 via Core Engine