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Target Snapshot

CHEMBL2363058 Target Snapshot

Iron · METAL

0Compounds
0Assays
0Approved Drugs
0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Iron shows approved-linked disease relevance led by myelodysplastic syndrome. 5 more disease programs remain visible in the same review block. 3 linked drugs keep the current disease frame grounded. Use myelodysplastic syndrome as the disease frame, then confirm a stable protein accession before cross-source reuse.

Review focus
Disease frame ready

Use myelodysplastic syndrome as the disease frame, then confirm a stable protein accession before cross-source reuse.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14 3 linked drugs
Open source guide
Disease program
myelodysplastic syndrome

Iron shows approved-linked disease relevance led by myelodysplastic syndrome. 5 more disease programs remain visible in the same review block. 3 linked drugs remain visible in the same block.

Start review with myelodysplastic syndrome because it currently carries approved-linked support. Linked drugs include CLIOQUINOL, DEFERASIROX, DEXRAZOXANE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Disease source · ChEMBL drug mechanism + indication proxy
Approved-linked Open Targets-ready proxy 3 linked drugs
Open disease block
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Iron as ChEMBL target CHEMBL2363058. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Iron
METAL
As of 2026-09-14
ChEMBL target ID
CHEMBL2363058
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Iron still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need to confirm why myelodysplastic syndrome is currently framed as approved-linked support. It currently carries 3 linked drugs in the same disease frame.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelIron
UniProt AccessionN/A

Iron

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Iron.

Review nameIron
Disease Relevance

Disease Relevance & Evidence Level

Open Targets-ready disease context using the current target-indication evidence contract.

Approved-linked Open Targets-ready proxy

Iron shows approved-linked disease relevance led by myelodysplastic syndrome. 5 more disease programs remain visible in the same review block.

Approved-linked Approved
myelodysplastic syndrome
3 linked drugs · 3 direct · 3 efficacy
Linked drugCLIOQUINOL
Linked drugDEFERASIROX
Linked drugDEXRAZOXANE
Approved-linked Approved
beta-thalassemia major
2 linked drugs · 2 direct · 2 efficacy
Linked drugDEFERASIROX
Linked drugEMERAMIDE
Approved-linked Approved
hemochromatosis
2 linked drugs · 2 direct · 2 efficacy
Linked drugDEFERASIROX
Linked drugDEFEROXAMINE MESYLATE
Approved-linked Approved
African iron overload
1 linked drug · 1 direct · 1 efficacy
Linked drugDEFERASIROX
Approved-linked Approved
amebiasis
1 linked drug · 1 direct · 1 efficacy
Linked drugCLIOQUINOL
Approved-linked Approved
Beta-thalassemia
1 linked drug · 1 direct · 1 efficacy
Linked drugDEFERASIROX
Source · ChEMBL drug mechanism + indication proxy
Review Cue

How to read disease relevance

Start review with myelodysplastic syndrome because it currently carries approved-linked support. Linked drugs include CLIOQUINOL, DEFERASIROX, DEXRAZOXANE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Lead diseasemyelodysplastic syndrome
Strongest levelApproved-linked
Block modeOpen Targets-ready proxy
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Source · ChEMBL 36 via Core Engine