Retinoic acid receptor · PROTEIN FAMILY · Homo sapiens
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As of 2026-09-13Retinoic acid receptor shows approved-linked disease relevance led by acne. 5 more disease programs remain visible in the same review block. 4 linked drugs keep the current disease frame grounded. Protein identity stays anchored to UniProt P13631. Start with acne, then reuse UniProt P13631 as the stable protein anchor across project notes and exports.
Start with acne, then reuse UniProt P13631 as the stable protein anchor across project notes and exports.
Retinoic acid receptor shows approved-linked disease relevance led by acne. 5 more disease programs remain visible in the same review block. 4 linked drugs remain visible in the same block.
Start review with acne because it currently carries approved-linked support. Linked drugs include ADAPALENE, ISOTRETINOIN, TAZAROTENE, TRETINOIN. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyRetinoic acid receptor gamma
Review this target as Retinoic acid receptor, mapped to UniProt P13631. ChEMBL maps the protein component as Retinoic acid receptor gamma. Sequence length is 454 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Retinoic acid receptor as ChEMBL target CHEMBL2363069, mapped to UniProt P13631. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Retinoic acid receptor is the right protein anchor across sources, using UniProt P13631 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why acne is currently framed as approved-linked support. It currently carries 4 linked drugs in the same disease frame.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Retinoic acid receptor |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | P13631 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Retinoic acid receptor gamma |
| UniProt Accession | P13631 |
| Component Type | Protein |
| Sequence Length | 454 aa |
Retinoic acid receptor gamma
Review this target as Retinoic acid receptor, mapped to UniProt P13631. ChEMBL maps the protein component as Retinoic acid receptor gamma. Sequence length is 454 aa.
Open Targets-ready disease context using the current target-indication evidence contract.
Retinoic acid receptor shows approved-linked disease relevance led by acne. 5 more disease programs remain visible in the same review block.
Start review with acne because it currently carries approved-linked support. Linked drugs include ADAPALENE, ISOTRETINOIN, TAZAROTENE, TRETINOIN. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL38 | 9.0 | EC50 | 1.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 9 | 0 | — |
| protein format | 5 | 1 | 9.0 |