Start with parasitic infection, then reuse UniProt E0W492 as the stable protein anchor across project notes and exports.
CHEMBL2364025 Target Snapshot
GABA-A receptor · PROTEIN COMPLEX GROUP · Pediculus humanus
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As of 2026-09-14GABA-A receptor shows approved-linked disease relevance led by parasitic infection. 1 more disease program remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Protein identity stays anchored to UniProt E0W492. Start with parasitic infection, then reuse UniProt E0W492 as the stable protein anchor across project notes and exports.
GABA-A receptor shows approved-linked disease relevance led by parasitic infection. 1 more disease program remain visible in the same review block. 1 linked drug remains visible in the same block.
Start review with parasitic infection because it currently carries approved-linked support. Linked drugs include LINDANE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyGaba-gated chloride channel, putative
Review this target as GABA-A receptor, mapped to UniProt E0W492. ChEMBL maps the protein component as Gaba-gated chloride channel, putative. Sequence length is 423 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats GABA-A receptor as ChEMBL target CHEMBL2364025, mapped to UniProt E0W492. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
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Start here when your first question is whether GABA-A receptor is the right protein anchor across sources, using UniProt E0W492 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why parasitic infection is currently framed as approved-linked support. It currently carries 1 linked drug in the same disease frame.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardBasic Information
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| Preferred Name | GABA-A receptor |
| Target Type | PROTEIN COMPLEX GROUP |
| Organism | Pediculus humanus |
| UniProt | E0W492 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Gaba-gated chloride channel, putative |
| UniProt Accession | E0W492 |
| Component Type | Protein |
| Sequence Length | 423 aa |
Gaba-gated chloride channel, putative
How to read this target
Review this target as GABA-A receptor, mapped to UniProt E0W492. ChEMBL maps the protein component as Gaba-gated chloride channel, putative. Sequence length is 423 aa.
Disease Relevance & Evidence Level
Open Targets-ready disease context using the current target-indication evidence contract.
GABA-A receptor shows approved-linked disease relevance led by parasitic infection. 1 more disease program remain visible in the same review block.
How to read disease relevance
Start review with parasitic infection because it currently carries approved-linked support. Linked drugs include LINDANE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.