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Target Snapshot

CHEMBL2364703 Target Snapshot

Tubulin · PROTEIN COMPLEX GROUP · Trichophyton

0Compounds
0Assays
0Approved Drugs
0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Tubulin shows approved-linked disease relevance led by candidiasis. 4 more disease programs remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Protein identity stays anchored to UniProt F2SZD3. Start with candidiasis, then reuse UniProt F2SZD3 as the stable protein anchor across project notes and exports.

Review focus
Review-ready target frame

Start with candidiasis, then reuse UniProt F2SZD3 as the stable protein anchor across project notes and exports.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13 1 linked drug
Open source guide
Disease program
candidiasis

Tubulin shows approved-linked disease relevance led by candidiasis. 4 more disease programs remain visible in the same review block. 1 linked drug remains visible in the same block.

Start review with candidiasis because it currently carries approved-linked support. Linked drugs include GRISEOFULVIN. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Disease source · ChEMBL drug mechanism + indication proxy
Approved-linked Open Targets-ready proxy 1 linked drug
Open disease block
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Tubulin as ChEMBL target CHEMBL2364703, mapped to UniProt F2SZD3. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Tubulin
PROTEIN COMPLEX GROUP · Trichophyton
As of 2026-09-13
ChEMBL target ID
CHEMBL2364703
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
F2SZD3
Tubulin beta chain
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Tubulin is the right protein anchor across sources, using UniProt F2SZD3 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need to confirm why candidiasis is currently framed as approved-linked support. It currently carries 1 linked drug in the same disease frame.

Jump to Disease Context
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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelTubulin beta chain
UniProt AccessionF2SZD3
Component TypeProtein
Sequence Length449 aa

Tubulin beta chain

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Tubulin, mapped to UniProt F2SZD3. ChEMBL maps the protein component as Tubulin beta chain. Sequence length is 449 aa.

Mapped IDF2SZD3
Review nameTubulin
OrganismTrichophyton
Disease Relevance

Disease Relevance & Evidence Level

Open Targets-ready disease context using the current target-indication evidence contract.

Approved-linked Open Targets-ready proxy

Tubulin shows approved-linked disease relevance led by candidiasis. 4 more disease programs remain visible in the same review block.

Approved-linked Approved
candidiasis
1 linked drug · 1 direct · 1 efficacy
Linked drugGRISEOFULVIN
Approved-linked Approved
infection
1 linked drug · 1 direct · 1 efficacy
Linked drugGRISEOFULVIN
Approved-linked Approved
tinea
1 linked drug · 1 direct · 1 efficacy
Linked drugGRISEOFULVIN
Approved-linked Approved
tinea
1 linked drug · 1 direct · 1 efficacy
Linked drugGRISEOFULVIN
Approved-linked Approved
tinea pedis
1 linked drug · 1 direct · 1 efficacy
Linked drugGRISEOFULVIN
Source · ChEMBL drug mechanism + indication proxy
Review Cue

How to read disease relevance

Start review with candidiasis because it currently carries approved-linked support. Linked drugs include GRISEOFULVIN. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Lead diseasecandidiasis
Strongest levelApproved-linked
Block modeOpen Targets-ready proxy
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Source · ChEMBL 36 via Core Engine