Use trypanosomiasis as the disease frame, then confirm a stable protein accession before cross-source reuse.
CHEMBL2366047 Target Snapshot
Kinetoplast DNA · NUCLEIC-ACID · Trypanosoma brucei
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Frame the target before identity details
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As of 2026-09-14Kinetoplast DNA shows approved-linked disease relevance led by trypanosomiasis. 5 more disease programs remain visible in the same review block. 2 linked drugs keep the current disease frame grounded. Use trypanosomiasis as the disease frame, then confirm a stable protein accession before cross-source reuse.
Kinetoplast DNA shows approved-linked disease relevance led by trypanosomiasis. 5 more disease programs remain visible in the same review block. 2 linked drugs remain visible in the same block.
Start review with trypanosomiasis because it currently carries approved-linked support. Linked drugs include PAFURAMIDINE MALEATE, PENTAMIDINE ISETHIONATE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyKinetoplast DNA
Review this target as Kinetoplast DNA.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Kinetoplast DNA as ChEMBL target CHEMBL2366047. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Start with the right source
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Kinetoplast DNA still has a stable protein naming contract across sources.
Jump to Protein ContextUse this block first when you need to confirm why trypanosomiasis is currently framed as approved-linked support. It currently carries 2 linked drugs in the same disease frame.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardBasic Information
Verify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Kinetoplast DNA |
| Target Type | NUCLEIC-ACID |
| Organism | Trypanosoma brucei |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
How to read this target
Review this target as Kinetoplast DNA.
Disease Relevance & Evidence Level
Open Targets-ready disease context using the current target-indication evidence contract.
Kinetoplast DNA shows approved-linked disease relevance led by trypanosomiasis. 5 more disease programs remain visible in the same review block.
How to read disease relevance
Start review with trypanosomiasis because it currently carries approved-linked support. Linked drugs include PAFURAMIDINE MALEATE, PENTAMIDINE ISETHIONATE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.