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Target Snapshot

CHEMBL2366150 Target Snapshot

NBsusSR · CELL-LINE · Homo sapiens

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51Compounds
1Assays
17Approved Drugs
51.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats NBsusSR as ChEMBL target CHEMBL2366150. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
NBsusSR
CELL-LINE · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL2366150
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether NBsusSR still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameNBsusSR
Target TypeCELL-LINE
OrganismHomo sapiens
ChEMBL ↗

Next Actions

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelNBsusSR
UniProt AccessionN/A

NBsusSR

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as NBsusSR.

Review nameNBsusSR
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

17
Approved
7
Phase III
6
Phase II
2
Phase I
Assay Mix

Activity Type Distribution

IC5051.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL65 9.71 IC50 0.1936 Preclinical
CHEMBL3545252 8.96 IC50 1.096 Approved
CHEMBL1972860 8.5 IC50 3.134 Clinical
CHEMBL159 8.49 IC50 3.232 Approved
CHEMBL1201182 7.67 IC50 21.34 Approved
CHEMBL1879463 7.61 IC50 24.6 Clinical
CHEMBL34259 7.53 IC50 29.58 Approved
CHEMBL603469 6.79 IC50 161.83 Clinical
CHEMBL1801204 6.77 IC50 170.19 Preclinical
CHEMBL2041933 6.5 IC50 318.19 Preclinical
Distribution

pChEMBL Value Distribution

9
5.0
6
5.5
7
6.0
3
6.5
0
7.0
3
7.5
1
8.0
2
8.5
0
9.0
1
9.5
pChEMBL
Approved Drugs

Approved Drugs

PALBOCICLIB
CHEMBL189963
Approved 2015
Properties Compare Identifier
TEMSIROLIMUS
CHEMBL1201182
Approved 2007
Properties Compare Identifier
GEFITINIB
CHEMBL939
Approved 2003
Properties Compare Identifier
DOCETAXEL
CHEMBL3545252
Approved 1995
Properties Compare Identifier
CYTARABINE
CHEMBL803
Approved 1969
Properties Compare Identifier
VINBLASTINE
CHEMBL159
Approved 1965
Properties Compare Identifier
METHOTREXATE
CHEMBL34259
Approved 1953
Properties Compare Identifier
Assay Landscape

Assay Landscape

1
Total Assays
51
Tested Compounds
1
Assay Types
Functional — 1 assays, 51 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 1 51 5.8

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine