DOHH-2 · CELL-LINE · Homo sapiens
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DOHH-2
Review this target as DOHH-2.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats DOHH-2 as ChEMBL target CHEMBL2366181. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | DOHH-2 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as DOHH-2.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL65 | 9.22 | IC50 | 0.6022 | Preclinical |
| CHEMBL213100 | 9.22 | IC50 | 0.5969 | Preclinical |
| CHEMBL159 | 8.74 | IC50 | 1.809 | Approved |
| CHEMBL513909 | 8.7 | EC50 | 2.0 | Clinical |
| CHEMBL1256459 | 8.65 | IC50 | 2.247 | Preclinical |
| CHEMBL413 | 8.47 | IC50 | 3.353 | Approved |
| CHEMBL553025 | 8.3 | IC50 | 5.039 | Approved |
| CHEMBL3545252 | 8.2 | IC50 | 6.303 | Approved |
| CHEMBL4462577 | 8.11 | IC50 | 7.7 | Preclinical |
| CHEMBL94657 | 8.08 | IC50 | 8.37 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 101 | 270 | 5.9 |
| organism-based format | 14 | 0 | — |