Cytochrome P450 14alpha-demethylase · SINGLE PROTEIN · Penicillium digitatum
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As of 2026-09-14Protein identity stays anchored to UniProt A1XG20. Use UniProt A1XG20 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt A1XG20 as the stable identity anchor, then attach disease evidence before program review.
sterol 14alpha-demethylase
Review this target as Cytochrome P450 14alpha-demethylase, mapped to UniProt A1XG20. ChEMBL maps the protein component as sterol 14alpha-demethylase. Sequence length is 516 aa.
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This review treats Cytochrome P450 14alpha-demethylase as ChEMBL target CHEMBL2366401, mapped to UniProt A1XG20. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cytochrome P450 14alpha-demethylase |
| Target Type | SINGLE PROTEIN |
| Organism | Penicillium digitatum |
| UniProt | A1XG20 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | sterol 14alpha-demethylase |
| UniProt Accession | A1XG20 |
| Component Type | Protein |
| Sequence Length | 516 aa |
sterol 14alpha-demethylase
Review this target as Cytochrome P450 14alpha-demethylase, mapped to UniProt A1XG20. ChEMBL maps the protein component as sterol 14alpha-demethylase. Sequence length is 516 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2228864 | 7.47 | Kd | 34.0 | Preclinical |
| CHEMBL2229713 | 7.34 | Kd | 46.0 | Preclinical |
| CHEMBL2229711 | 7.31 | Kd | 49.0 | Preclinical |
| CHEMBL2228870 | 7.2 | Kd | 63.0 | Preclinical |
| CHEMBL2228866 | 7.09 | Kd | 81.0 | Preclinical |
| CHEMBL2228880 | 7.05 | Kd | 90.0 | Preclinical |
| CHEMBL551746 | 6.92 | Kd | 120.0 | Preclinical |
| CHEMBL2228872 | 6.85 | Kd | 140.0 | Preclinical |
| CHEMBL2228868 | 6.82 | Kd | 150.0 | Preclinical |
| CHEMBL2228876 | 6.82 | Kd | 150.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 25 | 6.6 |
| assay format | 1 | 6 | 6.4 |