Use UniProt J3SE37 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2366442 Target Snapshot
cAMP-specific 3',5'-cyclic phosphodiesterase 4B · SINGLE PROTEIN · Crotalus adamanteus
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As of 2026-09-13Protein identity stays anchored to UniProt J3SE37. Use UniProt J3SE37 as the stable identity anchor, then attach disease evidence before program review.
Phosphodiesterase
Review this target as cAMP-specific 3',5'-cyclic phosphodiesterase 4B, mapped to UniProt J3SE37. ChEMBL maps the protein component as Phosphodiesterase. Sequence length is 563 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats cAMP-specific 3',5'-cyclic phosphodiesterase 4B as ChEMBL target CHEMBL2366442, mapped to UniProt J3SE37. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | cAMP-specific 3',5'-cyclic phosphodiesterase 4B |
| Target Type | SINGLE PROTEIN |
| Organism | Crotalus adamanteus |
| UniProt | J3SE37 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphodiesterase |
| UniProt Accession | J3SE37 |
| Component Type | Protein |
| Sequence Length | 563 aa |
Phosphodiesterase
How to read this target
Review this target as cAMP-specific 3',5'-cyclic phosphodiesterase 4B, mapped to UniProt J3SE37. ChEMBL maps the protein component as Phosphodiesterase. Sequence length is 563 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL858 | 4.13 | IC50 | 74000.0 | Clinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 5 assays, 2 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 2 | 4.1 |