Muscarinic acetylcholine receptor DM1 · SINGLE PROTEIN · Drosophila melanogaster
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As of 2026-09-14Protein identity stays anchored to UniProt P16395. Use UniProt P16395 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P16395 as the stable identity anchor, then attach disease evidence before program review.
Muscarinic acetylcholine receptor DM1
Review this target as Muscarinic acetylcholine receptor DM1, mapped to UniProt P16395. Sequence length is 805 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Muscarinic acetylcholine receptor DM1 as ChEMBL target CHEMBL2366467, mapped to UniProt P16395. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Muscarinic acetylcholine receptor DM1 is the right protein anchor across sources, using UniProt P16395 as the stable mapping.
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| Preferred Name | Muscarinic acetylcholine receptor DM1 |
| Target Type | SINGLE PROTEIN |
| Organism | Drosophila melanogaster |
| UniProt | P16395 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Muscarinic acetylcholine receptor DM1 |
| UniProt Accession | P16395 |
| Component Type | Protein |
| Sequence Length | 805 aa |
Muscarinic acetylcholine receptor DM1
Review this target as Muscarinic acetylcholine receptor DM1, mapped to UniProt P16395. Sequence length is 805 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL12980 | 9.3 | Ki | 0.5 | Preclinical |
| CHEMBL2251240 | 9.15 | Ki | 0.7 | Clinical |
| CHEMBL516476 | 8.74 | Ki | 1.8 | Clinical |
| CHEMBL279453 | 8.32 | Ki | 4.8 | Preclinical |
| CHEMBL76897 | 7.82 | Ki | 15.0 | Preclinical |
| CHEMBL9967 | 6.41 | Ki | 390.0 | Clinical |
| CHEMBL564226 | 6.29 | Ki | 510.0 | Preclinical |
| CHEMBL1617363 | 6.24 | Ki | 570.0 | Preclinical |
| CHEMBL59898 | 5.99 | Ki | 1030.0 | Preclinical |
| CHEMBL17045 | 5.91 | Ki | 1220.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 18 | 6.5 |
| assay format | 1 | 0 | — |