Pyruvate dehydrogenase complex · PROTEIN COMPLEX · Vigna radiata var. radiata
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As of 2026-09-14Protein identity stays anchored to UniProt P52902. Use UniProt P52902 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P52902 as the stable identity anchor, then attach disease evidence before program review.
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial
Review this target as Pyruvate dehydrogenase complex, mapped to UniProt P52902. ChEMBL maps the protein component as Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial. Sequence length is 397 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Pyruvate dehydrogenase complex as ChEMBL target CHEMBL2366570, mapped to UniProt P52902. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Pyruvate dehydrogenase complex |
| Target Type | PROTEIN COMPLEX |
| Organism | Vigna radiata var. radiata |
| UniProt | P52902 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial |
| UniProt Accession | P52902 |
| Component Type | Protein |
| Sequence Length | 397 aa |
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial
Review this target as Pyruvate dehydrogenase complex, mapped to UniProt P52902. ChEMBL maps the protein component as Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial. Sequence length is 397 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2227911 | 4.89 | IC50 | 12750.0 | Preclinical |
| CHEMBL2227928 | 4.71 | IC50 | 19700.0 | Preclinical |
| CHEMBL2227973 | 4.64 | IC50 | 23120.0 | Preclinical |
| CHEMBL2227682 | 4.02 | IC50 | 95380.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 11 | 4 | 4.6 |