Ecdysone receptor · PROTEIN COMPLEX · Nezara viridula
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As of 2026-09-15Protein identity stays anchored to UniProt E5L6Y1. Use UniProt E5L6Y1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt E5L6Y1 as the stable identity anchor, then attach disease evidence before program review.
Ecdysone receptor
Review this target as Ecdysone receptor, mapped to UniProt E5L6Y1. Sequence length is 444 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ecdysone receptor as ChEMBL target CHEMBL2366589, mapped to UniProt E5L6Y1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Ecdysone receptor |
| Target Type | PROTEIN COMPLEX |
| Organism | Nezara viridula |
| UniProt | E5L6Y1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ecdysone receptor |
| UniProt Accession | E5L6Y1 |
| Component Type | Protein |
| Sequence Length | 444 aa |
Ecdysone receptor
Review this target as Ecdysone receptor, mapped to UniProt E5L6Y1. Sequence length is 444 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2087139 | 7.0 | Ki | 100.0 | Preclinical |
| CHEMBL2087139 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL549789 | 6.7 | Ki | 200.0 | Preclinical |
| CHEMBL549789 | 6.6 | IC50 | 250.0 | Preclinical |
| CHEMBL224128 | 5.98 | IC50 | 1047.13 | Clinical |
| CHEMBL255034 | 5.86 | IC50 | 1380.38 | Preclinical |
| CHEMBL224128 | 5.6 | Ki | 2500.0 | Clinical |
| CHEMBL564971 | 5.22 | Ki | 6000.0 | Preclinical |
| CHEMBL564971 | 5.16 | IC50 | 7000.0 | Preclinical |
| CHEMBL226968 | 4.78 | Ki | 16800.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 5 | 7 | 5.5 |