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Target Snapshot

CHEMBL2367390 Target Snapshot

Chorioallantoic membrane · TISSUE · Gallus gallus

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221Compounds
135Assays
4Approved Drugs
70.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Chorioallantoic membrane as ChEMBL target CHEMBL2367390. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Chorioallantoic membrane
TISSUE · Gallus gallus
As of 2026-09-13
ChEMBL target ID
CHEMBL2367390
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Chorioallantoic membrane still has a stable protein naming contract across sources.

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Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameChorioallantoic membrane
Target TypeTISSUE
OrganismGallus gallus
ChEMBL ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelChorioallantoic membrane
UniProt AccessionN/A

Chorioallantoic membrane

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Chorioallantoic membrane.

Review nameChorioallantoic membrane
OrganismGallus gallus
Clinical Profile

Clinical Phase Distribution

4
Approved
1
Phase III
2
Phase II
Assay Mix

Activity Type Distribution

IC5070.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL53463 10.4 IC50 0.04 Approved
CHEMBL535 8.89 IC50 1.3 Approved
CHEMBL3298000 8.43 IC50 3.7 Preclinical
CHEMBL3297898 8.41 IC50 3.9 Preclinical
CHEMBL3297900 7.78 IC50 16.7 Preclinical
CHEMBL3297892 7.74 IC50 18.2 Preclinical
CHEMBL3297899 7.72 IC50 19.2 Preclinical
CHEMBL3297999 7.72 IC50 18.9 Preclinical
CHEMBL3297896 7.65 IC50 22.6 Preclinical
CHEMBL2105734 7.6 IC50 25.0 Clinical
Distribution

pChEMBL Value Distribution

8
5.0
13
5.5
8
6.0
2
6.5
6
7.0
7
7.5
2
8.0
1
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

SUNITINIB
CHEMBL535
Approved 2006
Properties Compare Identifier
ERLOTINIB
CHEMBL553
Approved 2004
Properties Compare Identifier
DOXORUBICIN
CHEMBL53463
Approved 1974
Properties Compare Identifier
Assay Landscape

Assay Landscape

135
Total Assays
52
Tested Compounds
3
Assay Types
Functional — 131 assays, 52 compounds
BAO Format Assays Compounds Avg pChEMBL
tissue-based format 73 31 6.5
cell membrane format 30 21 5.7
organism-based format 19 0 —
cell-based format 8 0 —
assay format 1 0 —
ADME — 2 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell membrane format 2 0 —
Toxicity — 2 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell membrane format 1 0 —
organism-based format 1 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine